Touchstone Diabetes Center
Researchers find shape-shifting fat cells can fuel breast cancer growth
In this episode of Science Café, Dr. Gupta discusses the problem of obesity and the enigma of why the expansion of fat tissue can lead to diabetes and metabolic syndrome in some individuals but not others. He also highlights how “fixing our fat” can break the link between obesity and diabetes or even protect against obesity itself. Learn how fat tissue is not our foe, but rather our friend. Dr. Gupta is an Associate Professor of Internal Medicine at UT Southwestern Medical Center, and joined the Touchstone Diabetes Center in 2012.
Find out how adipose progenitors respond to metabolic states: two fascinating papers (Jofﬁn and Shao) @CellStemCell reveal how adipose-tissue-resident PDGFRb+precursor cell fate is regulated by mitochondrial bio- energetics and how such processes go wrong in obesity pic.twitter.com/1pw35usUfL— Cell Biology UTSW (@CellUtsw) April 5, 2021
UTSW Study Links Alzheimer's-Related Protein To Diabetes And Obesity
A new study found a protein linked to Alzheimer’s Disease also contributes to problems with diabetes and obesity.
It’s called the amyloid precursor protein or APP. That’s the same amyloid believed to form plaque that may cause cognitive decline. The study, published in Nature Metabolism, found APP occurs in far higher levels in the fat cells of mice and humans who are obese. Follow the link to read more
"Plugged In To DFW 3: Obesity And Children"
Dr. Olga Gupta of UTSouthwestern Medical Center talks about Texas having the seventh highest obesity rate for youth ages 10 to 17.
Philipp E. Scherer, PhD
Professor and Director
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Olga Gupta M.D.
Pediatric diabetes care; Psychosocial mechanisms leading to poor adherence to diabetes self-management tasks in young individuals with type 1 diabetes; Molecular aspects of visceral adipose tissue mesothelial cells
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Christine Kusminski Ph.D.
Roger Unger M.D.
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Dayoung Oh Ph.D.
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Yingfeng Deng, Ph.D.
Rana Gupta, Ph.D.
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Ruth Gordillo, Ph.D.
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Jaime A. Davidson, M.D., F.A.C.P., F.A.C.E.
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