Touchstone Diabetes Center

Rodent Export information

ARC Rodent Export Procedure

Touchstone Diabetes Center Rodent request form: please fill out and email to

Kristin Dyer

Touchstone Diabetes Center

Mouse request form.

Resources for generating and characterizing mouse strains:

Gene-trap ES cell line resources:
International Gene-trap Consortium:    

German Gene Trap Consortium (Germany)  13031
Sanger Inst. Gene Trap Resource (Cambridge, UK) 7354
Soriano Lab Gene Trap Database (FHCRC, Seattle, USA)1627

Mouse suppliers:>
Federation of International Mouse Resources
Mutant Mouse Regional Resource Centers

Mouse resources:
Edinburgh Mouse Atlas (emap) and gene expression database (emage)
European Mouse Mutant Archive (EMMA)—transgenic mouse repository
Festing’s Inbred Strain Characteristics
Insitut Clinique de la Souris (ICS)
International Mouse Strain Resource—aims to list all publicly available mouse strainsa
Mouse Genome Informatics—access to data on the genetics, genomics, and biology of the mouse
Mouse Knockout and Mutation Database—searchable database—aims to facilitate international collaborative research among mouse users
Online Mendelian Inheritance in Man (OMIM)—catalogs relevant mouse models of human disease
TBASE—database for transgenic and knockout mice
The GeneNetwork—bioinformatic resources for systems genetics and complex trait analysis
Whole Mouse Catalog—information website

Jackson Lab’s Mouse Phenome Database:
Mouse Metabolic Phenotyping Centers (NIDDK):
EMPRESS (European consortium)
Examples of metabolic phenotyping tests and their standard operating procedures (SOPs)

Phenotype test                                                SOP website link
Energy expenditure    Body weight, food, and water intake        
Body composition                                 
Cold test                                              

Serum parameters      Cholesterol
Free fatty acids                                      
Bile Acids

Glucose tolerance      Intraperitoneal glucose tolerance test     
Meal tolerance test                              
Oral glucose tolerance test                   

Ex vivo                    General histology techniques                  
H&E staining                                       
Oil Red O staining                                

These protocols can be found on the EMPReSS website ( (Green et al.,  Bioinformatics 21: 2930-1, 2005).

Metabolic Pathways:
Kyoto Encyclopedia of Genes and Genomes:
Pathguide: the pathway resource list: (219 biological pathway resources)

Expression profiling:
Tissue distribution of most genes (Genomics Inst. Of the Novartis Res. Fnd):
Institute for Genomic Research
Gene Expression Omnibus
Jackson Laboratory
Brain Atlas
Real-time PCR probe and primer database:
Quantitative PCR primer database;

January issue of Nuclear Acids Research is the “Database Issue” each year.

Nuclear Receptor binding site identification:    Ref: Podvinec et al. NUBIScan, an in silico approach for prediction of nuclear receptor response elements. Molecular Endocrinology 16: 1269-1279, 2002.   Ref: Sandelin, et al. Prediction of Nuclear Hormone Receptor Response Elements.  Molecular Endocrinology 19:595-606, 2005.

Quantitative real-time PCR resources (primer databases):  Website for primer design algorithms. Website listing qPCR primers for human and mouse genes.  Ref: Spandido, et al. Nucleic Acids Research 38:D792-D799, 2010.   “QPDD” primer set (human and mouse/SG/TM) at NCI 
Ghent University ~3900 primer sets for multiple species, SG/TM    qPrimerDepot , mouse SG NCBI primer design and check website.

MicroRNA tools:   Website to search for miRNA targets. Website to search for human miRNA targets. Website to search for miRNA targets.

UT Southwestern Medical Center resources:
Home to NIDDK-sponsored mouse metabolic phenotyping center ( directed by Craig Malloy and Shawn Burgess to use NMR to measure metabolic flux
UT Southwestern Mouse Metabolic Core:
Visualsonics VEVO770 small animal ultrasound (Ralph Mason):
Seahorse extracellular flux (Scherer):